Table 1 Limit of detection (LOD) of each tumor biomarker by different biosensing techniques
From: Current research status of tumor cell biomarker detection
Sensing Technique | Target | Theory | LOD | Ref. |
|---|---|---|---|---|
Electrochemical | CTCs | Dual antibody recognition | 1 cell/mL | |
ctDNA | DNAzyme ratio assay | 25 aM | ||
exosomes | MOFs ECL assay | 9.08 × 103 particles/μL | ||
Fluorescence | CTCTs | CdTe QDs visual detection | 0.25 cells/mL | |
ctDNS | AgInS2/ZnS QDs & HCR amplification | 53 aM | ||
exosomes | Dual-selective MIP recognition | 2.43 × 106 particles/L | ||
telomerase | In situ fluorescence imaging | 1LoVo cell | ||
miRNA | TDFM nanoprobe recognition | 5 nM |
