Fig. 3: Overall survival by expression level of NRF2 in ESCC patients with dual-positive expression of NRF2 and NQO1.

A Comparison of overall survival between patients with the proportion of NRF2 expression in the nucleus more than 20% and those with less than 20%; B Comparison of overall survival between patients with NRF2 IHC score in the nucleus more than 20 and those patients with less than 20. P1 and P2 indicated P-value respectively calculated without and with adjusting for age, gender, tumor stage, smoking, and heavy alcohol consumption.