Fig. 1: Task design: aversive avoidance task (AV) and aversive extinction task (EV). | Molecular Psychiatry

Fig. 1: Task design: aversive avoidance task (AV) and aversive extinction task (EV).

From: Mechanisms underlying capsulotomy for refractory obsessive-compulsive disorder: neural correlates of negative affect processing overlap with deep brain stimulation targets

Fig. 1

In the AV task, two different cues (either aversive or neutral) indicating the valence of anticipation (AV_aversive/AV_neutral) were followed by three types of feedback images (AV_aversive/AV_grey/AV_neutral), with a target slide indicating the direction of button press in between. During aversive conditions, participants were shown grey images for correct and rapid response to the target slides, and negative images for incorrect or no response. During neutral conditions, neutral images were shown regardless of correctness or rapidity of responses. In the EV task, cues with single valence indicating aversive anticipation (EV_aversive) were followed by grey feedback images (EV_grey) regardless of correctness and rapidity of responses against target slides. The AV paradigm consists of 60 trials (with 30 aversive or neutral trials each presented in random order) in total, while the EV consists of 50. Note: Example for negative and neutral pictures is taken from the International Affective Picture System (IAPS).

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