Fig. 3: Proportion of variance explained by TRSs significantly associated with ADHD and by PRS.
From: Transcriptomic risk scores for attention deficit/hyperactivity disorder
Pseudo-R2 (in the y-axis) is presented for each TRS, TRS restricted to colocalized genes (TRScol), the PRS and the model that combines both scores (TRS + PRS or TRScol + PRS). Values in brackets indicate the best P-value threshold for a given tissue (P). Likelihood ratio test P-values for TRS and PRS vs. PRS-only model comparisons are given above the bars. Further statistical details can be found Supplementary Table S9.
