Fig. 5: Pharmacological and binding properties of the six antipsychotic drugs tested. | Molecular Psychiatry

Fig. 5: Pharmacological and binding properties of the six antipsychotic drugs tested.

From: Pharmacological fingerprint of antipsychotic drugs at the serotonin 5-HT2A receptor

Fig. 5

a Web representation of the potency (logIC50) and efficacy (% inhibition) of the six antipsychotics tested in the antagonist mode. b Principal component analysis of the antagonist mode (potency and efficacy) depicting the hierarchical clustering of the antipsychotics into three distinct groups. c Binding modes of the six antipsychotics at the 5-HT2AR.

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