Fig. 6: GWAS results for nociceptive threshold during the TF baseline session prior to heroin experience.

Regional association plots for (a) chromosome 2 and (b) chromosome 19. The top SNP identified for each chromosome is in purple with chromosome ___location indicated on the plot. The color of other SNPs corresponds to extent of linkage disequilibrium with the top SNP. Known genes of SNPs are indicated below the plots. Significance threshold: red line, p < 0.10; blue line, p < 0.05 (n = 874).