Fig. 4: Exploratory analysis of MOD effects on amygdala reactivity and the association with cognitive conflict performance. | Neuropsychopharmacology

Fig. 4: Exploratory analysis of MOD effects on amygdala reactivity and the association with cognitive conflict performance.

From: Modafinil enhances cognitive, but not emotional conflict processing via enhanced inferior frontal gyrus activation and its communication with the dorsomedial prefrontal cortex

Fig. 4

a Examining distinct conflict processes within separate groups revealed increased right amygdala activation following MOD treatment during cognitive relative to emotional conflict, and b enhancing effects were observed during cognitive but not emotional conflict. c In the MOD group accuracy was positively correlated with right amygdala activity during cognitive but not emotional conflict processing, whereas no association was observed in the PLC group. The filled curves show standard errors for each treatment group and the distribution curves in marginals indicate statistical densities of cognitive conflict performance and amygdala activity respectively. *p < 0.05. MOD modafinil, PLC placebo, IFG inferior frontal gyrus.

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