Fig. 1: Systemic baclofen dose-dependently suppresses punished alcohol self-administration in punishment-resistant rats. | Neuropsychopharmacology

Fig. 1: Systemic baclofen dose-dependently suppresses punished alcohol self-administration in punishment-resistant rats.

From: Activation of GABAB receptors in central amygdala attenuates activity of PKCδ + neurons and suppresses punishment-resistant alcohol self-administration in rats

Fig. 1

A Mean resistance score ( ± SEM). B Mean number of alcohol reinforcers (±SEM) earned during the 30 min punishment session on FR2 schedule in punishment-resistant (n = 14) and -sensitive rats (n = 14) receiving baclofen (0, 1, 3 mg/kg). C Mean inactive lever presses (±SEM) during the 30 min test. ***p < 0.001 compared to shock-sensitive rats; ##p < 0.01, ###p < 0.001 compared to vehicle.

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