Fig. 4: No significant associations between longitudinal changes in cortical structure (acAN-TP2-acAN-TP1) and changes in serum concentrations of the TNF-α cytokine. | Neuropsychopharmacology

Fig. 4: No significant associations between longitudinal changes in cortical structure (acAN-TP2-acAN-TP1) and changes in serum concentrations of the TNF-α cytokine.

From: Effect of serum concentrations of IL-6 and TNF-α on brain structure in anorexia nervosa: a combined cross-sectional and longitudinal study

Fig. 4

Left: Associations with CT changes. Right: Associations with lGI changes. Uncorrected statistical maps (p < 0.05) plotted on the inflated surface of the standard average subject and displaying regions in which differences in CT or lGI between acAN-TP2 and acAN-TP1 were associated with changes in TNF-α. The color scale shows p values expressed as −log10(p). Warm colors indicate a positive correlation between changes in TNF-α and CT or lGI. After FDR-correcting for multiple comparisons (q < 0.05) across each hemisphere and Bonferroni correcting across cytokine type, these associations were not significant. LH left hemisphere, RH right hemisphere. Colored outlines correspond to anatomical labels of the Desikan-Killiany atlas [44].

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