Fig. 3
From: A modified gene trap approach for improved high-throughput cancer drug discovery
HTS campaign. a The luciferase assay was miniaturized to a 1536-well format. b Clone SB01 was used to screen ~6000 compounds from several libraries, including the LOPAC, NPC and MIPE collections. The average Z′-factor for the screen was 0.7. c A scatter plot of the screening results demonstrates how well this assay performed. Blue dots represent BRAF inhibitors, red dots represent MEK inhibitors, and green dots represent ERK inhibitors
