Fig. 7 | Oncogene

Fig. 7

From: Regulatory networks in mechanotransduction reveal key genes in promoting cancer cell stemness and proliferation

Fig. 7

Schematic summary of the membrane pathway cancer mediated by TFs/miRNAs during the selection of TRCs. The membrane proteins affected by force from extracellular matrix (ECM) and lead to the change of downstream genes such as STAT3 and MYBL2. These TFs involved in the regulation of WNT/TGF-β/PI3K-AKT pathways and affected the expression of downstream cancer-related genes such as CCT3. CCT3, then affected the selection of TRCs

Back to article page