Fig. 1: Upregulation of G3BP2 is correlated with unfavorable outcome in ESCC patients. | Oncogene

Fig. 1: Upregulation of G3BP2 is correlated with unfavorable outcome in ESCC patients.

From: G3BP2 regulated by the lncRNA LINC01554 facilitates esophageal squamous cell carcinoma metastasis through stabilizing HDGF transcript

Fig. 1

A Big data mining from Oncomine (https://www.oncomine.org) and TCGA (https://www.cancer.gov) showed that G3BP2 was upregulated in ESCC. B mRNA expression of G3BP2 was examined by RT-qPCR using SYSUCC samples. GAPDH served as an internal control. C The protein expression of G3BP2 in immortalized esophageal epithelium cells (NE1) and ESCC cell lines. GAPDH acted as a loading control. D Representative images of G3BP2 staining in nontumor tissue and ESCC tissue microarray by immunohistochemistry analysis. Scale bar, up: 100 μm, down: 50 μm. E IHC score of G3BP2 staining in ESCCs and corresponding nontumor samples (n = 93). F and G Clinicopathologic correlation analyses of G3BP2 expression in ESCC. H Correlation between G3BP2 expression and overall survival was analyzed in the SYSUCC cohort by Kaplan-Meier curve analysis.

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