Table 1 Relationship between the MR of ZNF154 promotor and clinicopathologic parameters of 78 ESCC tissues.

From: Targeted demethylation at ZNF154 promotor upregulates ZNF154 expression and inhibits the proliferation and migration of Esophageal Squamous Carcinoma cells

  

ZNF154 methylation ratio

P value

Variables

Number of cases, %

High, % (MR > 48%),

Low, %(MR ≤ 48%),

Age, years old

 ≥61

44 (56.4)

21 (47.7)

23 (52.3)

0.475

 <61

34 (43.6)

19 (55.9)

15 (44.1)

 

Sex

 Male

65 (83.3)

36 (55.4)

29 (44.6)

0.188

 Female

13 (16.7)

4 (30.8)

9 (69.2)

 

Pathologic grade

   

0.865

 I

28 (35.9)

14 (50.0)

14 (50.0)

 

 II–III

50 (64.1)

26 (52.0)

24 (48.0)

 

TNM stage

   

0.249

 I–II

38 (48.7)

15 (39.5)

23 (60.5)

 

 III–IV

40 (51.3)

21 (52.5)

19 (47.5)

 

T stage

   

<0.05

 T1–2

21 (26.9)

5 (23.8)

16 (76.2)

 

 T3–4

57 (73.1)

31 (54.4)

26 (45.6)

 

N stage

   

0.438

 N0

34 (43.6)

14 (41.2)

20 (58.8)

 

 N1–3

44 (56.4)

22 (50)

22 (50)

 

Tumor ___location

   

0.650

 Upper/Middle

54 (69.2)

24 (44.4)

30 (55.6)

 

 Lower

24 (30.8)

12 (50)

12 (50)

 
  1. MR methylation ratio, TNM tumor-node-metastasis.
  2. P values were calculated using χ2 test, or Fisher’s exact test.
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