Fig. 1: GPx2 is overexpressed in GC and correlated with poor prognosis. | Oncogene

Fig. 1: GPx2 is overexpressed in GC and correlated with poor prognosis.

From: Glutathione peroxidase 2 knockdown suppresses gastric cancer progression and metastasis via regulation of kynurenine metabolism

Fig. 1

A, B GPx2 and GPx1 mRNA expression in GC in the GEPIA database. C The relationship between GPx2 mRNA expression and GPx1 mRNA expression in gastric cancer in the GEPIA database. D, E The relationship between GPx2 mRNA expression and KI67 or PCNA expression in the GEPIA database. F H-score of IHC showed GPx2 expression in gastric cancer tissues (n = 248) and paired paracancerous tissues (n = 213). G, H Survival analysis of the relationship between GPx2 expression and overall survival of GC patients in the GES 202831 (n = 875) and GES 239595 datasets (n = 631) in the Kaplan‒Meier Plotter database. I Survival analysis for the relationship between GPx2 expression and overall survival of GC patients in our cohort (n = 248). J Western blotting showing GPx2 and GPx1 protein expression in gastric cancer tissues and paired adjacent normal tissues (n = 5). K Representative IHC images of GPx2 expression in gastric cancer tissues and adjacent normal tissues (scale bar, 50 μm). *P < 0.05, **P < 0.01.

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