Fig. 1: Abnormal alternative splicing patterns in osteosarcoma. | Oncogene

Fig. 1: Abnormal alternative splicing patterns in osteosarcoma.

From: KPNA2 promotes osteosarcoma progression by regulating the alternative splicing of DDX3X mediated by YBX1

Fig. 1

A An analysis of the statistical characteristics of regulated AS events (RASEs) in osteosarcoma (P ≤ 0.05). B The statistical analysis determined the median proportion of SUVA AS ratio (pSAR) values associated with differential splicing events. C Principal component analysis (PCA) analysis established on RASEs of pSAR ≥ 50%. D Heatmap presented the ratio value of RASEs in three types of tissues (pSAR ≥ 50%). E The top 10 biological process GO enrichment analyses of regulated AS genes (pSAR ≥ 50%). The color scale displayed the row-scaled significance. F Venn diagram showed the overlap of RASEs between the primary vs. normal group and the metastatic vs. normal group.

Back to article page