Fig. 5: Enhanced tumor PD-L1 expression after irradiation treatment.
From: Targeting PD-L1 in non-small cell lung cancer using CAR T cells
a Signal intensities of PD-L1 expression in cell lines treated with 5 Gy radiation as analyzed by flow cytometry. b Percentage of PD-L1-positive cells and cell viability in A549 cells treated with different doses of radiation for 24 or 48 h. c The effect of radiation treatment on anti-tumor efficacy of PD-L1-CAR T cells at different effector (E): target (T) ratios. Data represented technical triplicates using T cells from one donor and were shown as mean ± SEM. *p ≤ 0.05, **p ≤ 0.01, ****p ≤ 0.0001, ns not significant.
