Fig. 5: Clonal evolution pattern predicts response to progression-free survival in patients. | Oncogenesis

Fig. 5: Clonal evolution pattern predicts response to progression-free survival in patients.

From: Exploring potential molecular resistance and clonal evolution in advanced HER2-positive gastric cancer under trastuzumab therapy

Fig. 5

A Example fishplot for patients with extensive branching, single branching, and linear evolution patterns. Radiology imaging of the tumor site in each corresponding patient was displayed in relation to the time point when the image was captured. Sex, age, best response to treatment, PFS, and OS for each patient was shown above the corresponding fishplot. B Hazard of extensive branching pattern over other evolutionary patterns with PFS or C OS as the endpoint. SD stable disease, PR partial response, PD progressive disease.

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