Table 4 Risks of overweight and high adiposity at age 4 years in relation to infancy weight growth trajectories in LGA and AGA children.

From: Fetal overgrowth and weight trajectories during infancy and adiposity in early childhood

Infancy growth trajectory

 

Low growth (1)

Mid growth (2)

High growth (3)

Adjusted Pa

OR (95% CI)a

1 vs. 2

3 vs. 2

Overweight/obesity, n (%)

AGA

48 (10.3)

135 (14.8)

106 (35.7)

0.0008

0.69 (0.35, 1.36)

2.67 (1.60, 4.44)

LGA

6 (9.5)

43 (29.5)

29 (58.0)

0.002

0.30 (0.05, 1.89)

4.30 (1.10, 16.77)

High adiposity, n (%)

AGA

50 (10.9)

157 (17.2)

100 (33.7)

0.003

0.67 (0.38, 1.18)

2.18 (1.28, 3.71)

LGA

6 (9.7)

41 (28.1)

22 (44.0)

0.04

0.29 (0.05, 1.86)

2.57 (0.65, 10.10)

  1. Data presented are n (%) or the OR (odds ratio) with 95% CI (confidence interval) comparing the high- or low- to mid-growth (reference) trajectory. Overweight/obesity: BMI for sex and age >85th percentile; High adiposity: percent body fat for sex and age >85th percentile. Tests for interaction between growth trajectory and LGA/AGA status: P < 0.0001 for overweight/obesity, P = 0.0003 for high adiposity.
  2. LGA large-for-gestational age (birth weight >90th percentile), AGA appropriate-for-gestational age (birth weight 10th–90th percentiles).
  3. aP values and ORs were adjusted for maternal (pre-pregnancy BMI, education, alcohol in pregnancy, gestational diabetes mellitus) and infant (cesarean section, sex, gestational age, breast feeding) characteristics; other co-variables did not affect the comparisons.
  4. P values and ORs in bold: P < 0.05.
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