Table 4 Sex-specific associations between HPA-axis CpGs and antenatal steroid exposure in ELGAN ECHO males (N = 194) after adjustment for potential confoundersa.

From: Epigenetic associations in HPA axis genes related to bronchopulmonary dysplasia and antenatal steroids

CpG site

Gene

Coefficients

p value

FDR < 5%

cg26981809

FKBP5

−0.0200

2.49E−06

0.0007

cg02757179

POMC

0.0791

3.43E−05

0.0050

  1. FDR false discovery rate, HPA hypothalamic-pituitary-adrenal.
  2. aCoefficients are the slope of the relationship after adjustments for potential confounders: gestational age (GA) at birth, sex, study site, outborn status, fetal growth restriction, maternal age, maternal smoking during pregnancy, and cell type proportions (CD8 T cells, CD4 T cells, natural killer cells, B cells, monocytes, granulocytes, and nRBCs).
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