Fig. 4 | Signal Transduction and Targeted Therapy

Fig. 4

From: A20 promotes colorectal cancer immune evasion by upregulating STC1 expression to block “eat-me” signal

Fig. 4

A20 impaired the phagocytosis function of macrophages to mediate tumor immune evasion. a The experimental scheme of the animal study. b The images of tumors excised from NSG mice at the end of experiments. c Tumor weights of the two treatment groups, n = 5. d Tumor growth curves of the two treatment groups, n = 5. e The experimental scheme of the animal experiment using BALB/C mice. f The images of tumors excised from BALB/C mice at the end of experiments. g Tumor weights of different groups, n = 6. h, i Tumor growth curves, n = 6. j, k The infiltration of macrophages (F4/80+) in mice tumor tissues (X400), n = 6

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