Fig. 3

Elevated levels of RIPK1 and IL-8 in circulating serum of ALS patients. a, b Plotted RIPK1 and IL-8 levels in the serum of individual healthy control (n = 63) and baseline of ALS patients (n = 189). Graph (a, b) were plotted in Prism 8 showing mean values with SD. Statistical test used Mann-Whitney test, ****P < 0.0001. c Data were Natural Log transformed prior to analysis. Serum RIPK1 levels were positively associated with serum IL-8 levels (n = 189) (Spearman correlation coefficient, r = 0.3123, with ****P < 0.0001)