Fig. 9
From: The multiple roles of interferon regulatory factor family in health and disease
The potential role of IRFs in inflammatory and autoimmune diseases. The reported IRF family members show protective roles, negative roles, or dual roles in inflammatory bowel disease, psoriasis, systemic lupus erythematosus, and multiple sclerosis. On the other hand, the reported IRF family members almost play negative functions on atopic dermatitis, asthma, Sjögren’s syndrome and rheumatoid arthritis
