Fig. 9 | Signal Transduction and Targeted Therapy

Fig. 9

From: Clinical investigation on nebulized human umbilical cord MSC-derived extracellular vesicles for pulmonary fibrosis treatment

Fig. 9

Clinical efficacy of nebulized hUCMSC-EVs in the therapy of pulmonary fibrosis. Levels and statistical analyses of FVC (a), MVV (b), SGRQ (c), and LCQ (d) before and after the treatment with nebulized saline and hUCMSC-EVs in the clinical trial. e A heatmap displaying the benefit cases from the treatment with nebulized saline and hUCMSC-EVs. Orange color indicates improvement, while blue color indicates no improvement. The numbers correspond to the case identifiers. (1: improved > unimproved; 0.5: improved = unimproved; 0: improved < unimproved) f Representative HRCT images of the lungs of three participants. FVC Forced Vital Capacity, MVV Maximal Voluntary Ventilation, SGRQ St. George’s Respiratory Questionnaire, LCQ Leicester Cough Questionnaire

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