Fig. 2: Differential effect of ST8SIA2-protective haplotype on fractional anisotropy in healthy controls and subjects with schizophrenia | Translational Psychiatry

Fig. 2: Differential effect of ST8SIA2-protective haplotype on fractional anisotropy in healthy controls and subjects with schizophrenia

From: Differential effect of disease-associated ST8SIA2 haplotype on cerebral white matter diffusion properties in schizophrenia and healthy controls

Fig. 2

The pink cluster (804 voxels) located on the right corona radiata and the superior longitudinal fasciculus represents voxels showing a significant interaction between ST8SIA2 protective haplotype and diagnosis of schizophrenia on fractional anisotropy. MNI coordinates are given on the top of each slice. The cluster is significant at the whole brain level (corrected p = 0.04, family-wise error rate-corrected). The Tukey Box-And-Whiskers plot represents the distribution of the mean FA values extracted from the pink cluster, with whiskers representing 1.5 interquartile range. Healthy controls (HC, n = 172, blue) and subjects with schizophrenia (SCZ, n = 281, red) carrying one or two copies (1) or no copy (0) of the ST8SIA2-protective haplotype are shown. Results of the post hoc tests are indicated: *p < 0.05; **p < 0.01

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