Fig. 5: Glutamate release from PFC gliosomes. | Translational Psychiatry

Fig. 5: Glutamate release from PFC gliosomes.

From: Changes at glutamate tripartite synapses in the prefrontal cortex of a new animal model of resilience/vulnerability to acute stress

Fig. 5

A Basal and (B) 15 mM KCl-evoked [3H]-Asp release measured immediately after FS (40 min from the beginning of stress). Unpaired student’s t-test; N = 5 (CNT), 6 (FS). C Basal and (D) 15 mM KCl-evoked [3H]-Asp release measured 6 h after the beginning of FS. Unpaired student’s t-test; N = 8 (CNT), 6 (FS). E Basal and (F) 15 mM KCl-evoked [3H]-Asp release measured 24 h after the beginning of FS. Unpaired student’s t-test; N = 11 (CNT), 30 (FS). G Basal and (H) 15 mM KCl-evoked [3H]-Asp release measured 24 h after the beginning of FS with separation in FS-R and FS-V. One-way ANOVA, Tukey’s post-hoc test: p < 0.05. N = 11 (CNT), 11 (FS-R), 19 (FS-V), *p < 0.05. I Basal and (J) 15 mM KCl-evoked [3H]-Asp release measured in physiological conditions (physiological medium, PM) or in presence of calcium free medium, 10 µM DL-TBOA or 10 µM KB-R7943 24 h after the beginning of FS in CNT and FS-V. Two-way ANOVA, Tukey’s post-hoc test: p < 0.05. N = 5 (CNT), 5 (FS-V), *p < 0.05, **p < 0.01, ***p < 0.001 and ****p < 0.0001.

Back to article page