Fig. 5: Diagnosing MDD subgroups from gut microbiome features.

A–C Based on the importance value of random forest analysis (>2%) between MDD subgroups and HCs, 37 species was identified (see Table S2–4 for importance value). This microbial panel enabled the differentiation between any 2 subgroups with high diagnostic accuracy (AUC, 0.992–0.998).