Fig. 1 | Bone Research

Fig. 1

From: Secreted frizzled related-protein 2 (Sfrp2) deficiency decreases adult skeletal stem cell function in mice

Fig. 1

Analysis of scRNA-seq data from previously published datasets29 that assessed non-hematopoietic cell lineages of mouse bone marrow in steady state conditions. a tSNE plot of cre-induced osteoblasts (Col2.3+; red), mesenchymal stromal cells (Lepr+; green), and vascular cells (VE-Cad+; blue) and (b) associated clusters. c, d Sfrp2-expressing cells were found to be significantly enriched in cluster 2, a cluster containing the Lepr+ skeletal stem/progenitors (termed “mesenchymal stromal” cell population by the authors) that also exhibited the greatest number of cells with a high magnitude of Lepr expression

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