Fig. 9 | Bone Research

Fig. 9

From: FGF signaling modulates mechanotransduction/WNT signaling in progenitors during tooth root development

Fig. 9

Schematic of FGF signaling in progenitor cells regulating mechanotransduction and WNT signaling to modulate proliferation and differentiation during tooth root development. Loss of Fgfr1 in Gli1+ progenitor cells leads to increased and ectopic Piezo2 expression, which activates WNT signaling through Fzd6/β-catenin and Piezo2/β-catenin. Schematic was created with BioRender

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