Table 3 Baseline characteristics between patients with thrombosis who underwent cytoreductive nephrectomy (CN) and did not undergo CN.

From: The role of cytoreductive nephrectomy and systemic therapy in the management of tumour thrombus in patients with metastatic renal cell carcinoma

Covariate

Full sample

(n = 64)

No surgery

(n = 18)

Cytoreductive nephrectomy (n = 46)

p-valuea

Age

   

0.087

 Median (Q1, Q3)

58.6 (50.0,66.4)

61.4 (55.1,69.6)

57.1 (48.6,63.8)

 

Gender

   

0.53

 Female (n, %)

15 (23)

3 (17)

12 (26)

 

 Male (n, %)

49 (77)

15 (83)

34 (74)

 

Histology

   

0.11

 Clear cell (n, %)

44 (69)

14 (78)

30 (65)

 

 Non-clear cell (n, %)

19 (30)

3 (17)

16 (35)

 

 Unclassified tumour (n, %)

1 (2)

1 (6)

0 (0)

 

No of metastatic sites

 >1 (n, %)

48 (75)

15 (83.3)

33 (68.8)

0.52

 1 (n, %)

16 (25)

3 (16.7)

13 (27.1)

 

KPS

   

0.61

 <80 (n, %)

24 (37.5)

5 (27.8)

10 (21.7)

 

 >=80 (n, %)

40 (62.5)

13 (72.2)

36 (78.3)

 

IMDC category

   

0.55

 Favourable (n, %)

3 (5)

0 (0)

3 (7)

 

 Intermediate/poor (n, %)

61 (95)

18 (100)

43 (93)

 

Mayo classification

   

0.4

 0 (n, %)

31 (50)

13 (72.2)

20 (43)

 

 I (n, %)

7 (11)

0 (0)

7 (15)

 

 II (n, %)

9 (15)

2 (12)

7 (15)

 

 III (n, %)

11 (18)

2 (12)

9 (20)

 

 IV (n, %)

4 (6)

1 (6)

3 (7)

 

Systemic therapy

 Sunitinib (n, %)

48

14

34

 

 Sorafenib (n, %)

5

1

4

 

 Pazopanib (n, %)

2

2

0

 

 Chemotherapy (n, %)

3

1

2

 

 Nivolumab-ipilimumab (n, %)

5

0

5

 

 Bevacizumab Erlotinib (n, %)

1

0

1

 
  1. IMDC International Metastatic Renal Cell carcinoma Database Consortium, KPS Karnofsky Performance Score.
  2. aComparison between surgery and no surgery group.