Fig. 4: Establishment and verification of the NPC prognostic signature. | British Journal of Cancer

Fig. 4: Establishment and verification of the NPC prognostic signature.

From: Identification of novel molecular subtypes to improve the classification framework of nasopharyngeal carcinoma

Fig. 4

a Heatmap of the correlation between module eigengenes and subtypes of NPC. Each table cell contains the correlation coefficient and p-value. The color shade represents the correlation coefficient and p-value is described in parenthesis. b Univariate Cox analysis of key genes identified by WGCNA in three subtypes. c Lasso Cox analysis uncovered nine genes most associated with DFS. The best parameter (λ) was selected based on the LASSO algorithm. d Risk scores distribution, survival status of each patient, and heatmap of nine prognostic risk genes expression. Kaplan–Meier curves for patients with high- or low-risk scores in the in-house training cohort (e) and GSE102349 testing cohort (f). DFS is selected as a statistical indicator.

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