Fig. 4: Single-cell level deconvolution of colorectal cancer tissue. | British Journal of Cancer

Fig. 4: Single-cell level deconvolution of colorectal cancer tissue.

From: Differential cellular origins of the extracellular matrix of tumor and normal tissues according to colorectal cancer subtypes

Fig. 4

a The bulk transcriptomic data of TCGA samples were deconvoluted with 33 cell states by CIBERSORTX analysis tool and annotated with consensus molecular subtype (CMS) by CMSclassifier. Normalized cell fraction values of each cell type with CMS annotation were expressed in the heatmap. Violin plot of b NAT enriched cell types and c tumor enriched cell types. p-values were calculated using one-way ANOVA. d Heatmap of correlation between CMS probability and proportion of each cell state. The coefficients of Pearson correlation were calculated with each cell state and probability value of each CMS. e Dot plot of CMS probability and the proportion of each cell state. Each dot represents each sample in TCGA samples.

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