Fig. 3: PZH inhibited LYVE-1, VEGF-C, and VEGFR-3 expression in vivo. | Cancer Gene Therapy

Fig. 3: PZH inhibited LYVE-1, VEGF-C, and VEGFR-3 expression in vivo.

From: ANRIL promotes the regulation of colorectal cancer on lymphatic endothelial cells via VEGF-C and is the key target for Pien Tze Huang to inhibit cancer metastasis

Fig. 3

A, D Expression of LYVE-1, VEGF-C, and VEGFR-3 in subcutaneous xenograft tumor tissues (A) and orthotopic xenograft tumor tissues (D), Data represent the mean ± SEM of experiments conducted on 3 mice. ***, ****P < 0.01 in comparison with the control group. B, E Expression of VEGF-C and VEGFR-3 in xenograft tumor tissues (B) and orthotopic xenograft tumor tissues (E). Data represent the mean ± SEM of experiments conducted on 3 mice. *P < 0.05; **P < 0.01 in comparison with the control group. C, F VEGF-C content in the serum of mice with subcutaneous xenograft tumor (C) and orthotopic xenograft tumor (F). Data represent the mean ± SEM of experiments conducted on 6 mice. ***P < 0.01 in comparison with the control group.

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