Fig. 7: Transcriptomics analysis changes of transcriptional level in PZH-treated tumor-bearing mice with orthotopic tumor transplantation, and HCT-8 cells with ANRIL overexpression. | Cancer Gene Therapy

Fig. 7: Transcriptomics analysis changes of transcriptional level in PZH-treated tumor-bearing mice with orthotopic tumor transplantation, and HCT-8 cells with ANRIL overexpression.

From: ANRIL promotes the regulation of colorectal cancer on lymphatic endothelial cells via VEGF-C and is the key target for Pien Tze Huang to inhibit cancer metastasis

Fig. 7

A Volcano plots was used to compare gene expression profiles in Control (Model) vs. PZH (Model + PZH) (|fold change| ≥ 1.5, P < 0.05). B Pathway enrichment analysis was performed to identify the related Reactome pathways in Control (Model) vs. PZH (Model + PZH). C Volcano plots was used to compare gene expression profiles in Vector (HCT-8/Vector) vs. ANRIL OE (HCT-8/ANRIL) (|fold change| ≥ 1.5, P < 0.05). D The pathway enrichment analysis was performed to identify the related Reactome pathways in Vector (HCT-8/Vector) vs. ANRIL OE (HCT-8/ANRIL).

Back to article page