Fig. 3: Impaired differentiation of thymic Treg cells in Kdm6bfl/flFoxn1-Cre thymus. | Cell Death & Differentiation

Fig. 3: Impaired differentiation of thymic Treg cells in Kdm6bfl/flFoxn1-Cre thymus.

From: Critical role of histone H3 lysine 27 demethylase Kdm6b in the homeostasis and function of medullary thymic epithelial cells

Fig. 3

a Flow cytometry analysis of CD4, CD8, CD25 and CD44 expression by thymocytes from Kdm6bfl/flFoxn1-Cre and wild-type mice for the cell surface marker (n = 6 per genotype). b Flow cytometry analysis of thymic Treg cells from Kdm6bfl/flFoxn1-Cre and wild-type mice (n = 6 per genotype). c Percentages of Treg cells in the thymus (top) and spleen (bottom) (n = 6 per genotype). d Flow cytometry analysis of CD4, CD8, CD44 and CD62L expression by splenocytes from Kdm6bfl/flFoxn1-Cre and wild-type mice (n = 6 per genotype). e Flow cytometry analysis of Treg cells in the spleens from Kdm6bfl/flFoxn1-Cre and wild-type mice (n = 6 per genotype).

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