Fig. 4: Knockdown of linc00665 promotes cell cycle arrest and induces cell apoptosis in vitro. | Cell Death & Disease

Fig. 4: Knockdown of linc00665 promotes cell cycle arrest and induces cell apoptosis in vitro.

From: Long non-coding RNA linc00665 promotes lung adenocarcinoma progression and functions as ceRNA to regulate AKR1B10-ERK signaling by sponging miR-98

Fig. 4

a, b Flow cytometric analysis of cell cycle distributions in A549 and H1299 cells after transfection with linc00665 siRNA. c, d Flow cytometric analysis of apoptosis in A549 and H1299 cells after transfection. e Expression of Bcl-2, Bax, Caspase-3, PARP, and GAPDH protein in A549 and H1299 cells after transfection with linc00665 siRNA. NC negative control; *p < 0.05, **p < 0.01

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