Fig. 1: Differentiation-induced pluripotent stem cells (iPSCs) into Leydig-like cells (iPSC-LCs) based on molecular compounds.

a The schematic illustration of differentiation protocol of iPSC-LCs. b Morphological changes in the differentiation of iPSC-LCs under inverted microscope on day 25. c The transmission electron microscopy (TEM) in different group cells. White arrows point to lipid droplets. d Medium testosterone (T) levels in different groups by radioimmunoassay. Mean ± SE, n = 5. *P < 0.05, **P < 0.01, designate significant differences