Fig. 3: SQ1and SQ2 induced Golgi localization of LC3.
From: Squaramide-based synthetic chloride transporters activate TFEB but block autophagic flux
Representative images and statistical analysis of U2OS cells expressing GFP-GALT RFP-LC3 cells treated with torin (300 nM), oleate (500 μM), SQ1, SQ2 or SQ3 (10 μM) for 6 h. Quantitative analysis represents the number and area of GALT1+ Golgi structures per cell and the colocalization of LC3+ and GALT1+ structures. Data are expressed as means ± SD of one representative experiment (***p < 0.0001, compared to untreated cells, Co). Representatie images are showin in panel a and quantitative comparisions are detailled in panel b
