Fig. 2: CPCs-Ex reduce the CVB3-induced H9C2 cell apoptosis in vitro. | Cell Death & Disease

Fig. 2: CPCs-Ex reduce the CVB3-induced H9C2 cell apoptosis in vitro.

From: Exosomes derived from cardiac progenitor cells attenuate CVB3-induced apoptosis via abrogating the proliferation of CVB3 and modulating the mTOR signaling pathways

Fig. 2

H9C2 cells were collected at 12, 24, and 48 h after infected with CVB3. a Depressed apoptosis rate of H9C2 cells in Exos groups compared with control (mean ± SEM, n = 3, one-way ANOVA). b, c Depressed mRNA and protein level of VP1 in Exos groups compared with control (mean ± SEM, n = 3, one-way ANOVA). d CPC-EX blocked CVB3-induced Bim and Bax activation and cleavage of caspase-9 and caspase-3 and promoting the expression of BcL-2 (mean ± SEM, n = 3, one-way ANOVA). *P < 0.05 vs. Control

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