Fig. 4: Zmat3 loss does not accelerate mutant KrasG12D-driven lung adenocarcinoma.
From: Consequences of Zmat3 loss in c-MYC- and mutant KRAS-driven tumorigenesis
a Representative low magnification H&E stained lungs of KrasG12D/+ (K), KrasG12D/+;p53−/− (KPnull) and KrasG12D/+;Zmat3−/− (KZ) mice 6- and 10-weeks following i.n. administration of Ad5-CMV-Cre. Scale, 1 mm. b Lesion classification in the lungs of K (n = 4), KPnull (n = 4) and KZ (n = 5) mice 10 weeks following i.n. Ad5-CMV-Cre infection. c Wet weight (mg) of the left lung lobe of K (n = 3), KPnull (n = 3) and KZ (n = 8) mice 6 weeks following i.n. Ad5-CMV-Cre infection. Violin plot indicates the median weight and distribution.
