Fig. 3: NSUN2 promoted human gastric cancer tumorigenesis in vivo.

NSUN2 overexpress cells, NSUN2 knockdown cells and corresponding wild-type cells were injected into female nude mice subcutaneously. a, d Tumor-bearing mice and tumors were shown. Data were showed as the mean ± SD; *p < 0.05. b, e Tumor size and weight were measured after 3 weeks. Data were showed as the mean ± SD; *p < 0.05. c, f HE and IHC staining of NSUN2, p57Kip2, and Ki-67 expression in tumor sections at ×200 magnification. Scale bars indicated 10 μm.