Fig. 2: Cardioprotective effects of hCVPC-EVs delivered to acutely infarcted murine hearts by permanent ligation of the LAD coronary artery. | Cell Death & Disease

Fig. 2: Cardioprotective effects of hCVPC-EVs delivered to acutely infarcted murine hearts by permanent ligation of the LAD coronary artery.

From: Extracellular vesicles from human embryonic stem cell-derived cardiovascular progenitor cells promote cardiac infarct healing through reducing cardiomyocyte death and promoting angiogenesis

Fig. 2

a Schematic of treatment and analysis using hCVPC-extracellular vesicles. b Echocardiographic analysis of LVEF and LVDs. n = 8 (PBS), 8 (EV-N), and 11 (EV-H). c Representative cross-sectional images and quantitative data of hearts stained with Masson’s trichrome at day 28 post MI. n = 6–8. Scale bars, 1 mm. d In vivo PET/CT images at day 28 post MI. *p < 0.05, **p < 0.01, ***p < 0.001.

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