Fig. 5: Cpeb3 mutation induces POI in mice. | Cell Death & Disease

Fig. 5: Cpeb3 mutation induces POI in mice.

From: CPEB3 deficiency in mice affect ovarian follicle development and causes premature ovarian insufficiency

Fig. 5

A Quantification of CL in 3- and 9-month-old WT and Cpeb3-mutant ovaries per section. B Representative images of in vivo matured eggs from WT and Cpeb3-mutant mice. C The number of eggs obtained from WT and Cpeb3-mutant mice per mice. D Serum levels of FSH in 3- and 9-month-old female mice. E Serum levels of E2 in 3- and 9-month-old female mice. F POI relative mRNA levels were performed by qRT-PCR in ovaries from 3-month-old female mice. Scale bar = 153 μm in B. Data were represented as the mean ± SD, n = 5 in A, three in B and F, six in D and E. *P < 0.05, **P < 0.01, ****P < 0.0001, ns. P > 0.05.

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