Fig. 5: In the SCAT of golden hamsters, the macrophages around dead adipocytes are infected with SARS-CoV-2 and formed syncytia.
From: SARS-CoV-2 infection induces persistent adipose tissue damage in aged golden Syrian hamsters
A Representative IHC staining for SARS-CoV-2 spike protein (brown precipitate) in the (inguinal) SCAT of young-adult and aged hamsters at 0 (mock), 7 and 22 dpi (scale bars = 100 μm). Higher magnification images of CLSs are shown (scale bars = 50 μm). Slides were counterstained with Mayer’s hematoxylin. B The same CLSs found in the (inguinal) SCAT of young-adult and aged hamsters at, respectively, 7 and 22 dpi, were H&E-stained (left panels) or DAPI-stained (right panels) (scale bars = 50 μm). In left panels, the blue fluorescence indicates DAPI staining for cell nuclei, and higher magnifications are shown that revealed the presence of multinucleated cells.
