Fig. 8: Lipidomic landscape of LLC tumors under SULT2B1b or PFM037 perturbation. | Cell Death & Disease

Fig. 8: Lipidomic landscape of LLC tumors under SULT2B1b or PFM037 perturbation.

From: Harnessing the reverse cholesterol transport pathway to favor differentiation of monocyte-derived APCs and antitumor responses

Fig. 8

A Score plot by partial least squares-discriminant analysis (PLS-DA) related to the lipidic fraction of Mock and SULT2B1b-LLC tumors (n = 5 tumors/group). B Variable importance in projection (VIP) plot showing the top 10 NMR signals resulted more statistically different in the lipidic fractions of Mock- and SULT2B1b-LLC tumors in C57Bl/6 mice (n = 5 tumors/group). C Box plots showing the levels of lipid species, evaluated as normalized proton signals, differentially expressed by Mock- and SULT2B1b-LLC tumors (n = 5 tumors/group). D Score plot by partial least squares-discriminant analysis (PLS-DA) related to the lipidic fraction of vehicle- and PFM037-treated-LLC tumors (n = 5 tumors/group). E Variable importance in projection (VIP) plot showing the top 10 NMR signals resulted more statistically different in the lipidic fractions of vehicle- and PFM037-treated-LLC tumors in C57Bl/6 mice (n = 5 tumors/group). F Box plots showing the levels of lipid species, evaluated as normalized proton signals, differentially expressed by LLC tumors from mice treated with vehicle of PFM037 (n = 5 tumors/group).

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