Fig. 6: cIAP2/NFκB signaling is activated in response to chemotherapy to promote anastasis. | Cell Death & Disease

Fig. 6: cIAP2/NFκB signaling is activated in response to chemotherapy to promote anastasis.

From: Anastasis enhances metastasis and chemoresistance of colorectal cancer cells through upregulating cIAP2/NFκB signaling

Fig. 6

A The protein levels of cIAP2, p-p65, and p65 in HCT-116CasE or HT-29CasE cells treated with PTX for 24 h (treated) and recovered for 12 h or 24 h. B The effect of knocking down BIRC3 on the percentage of ZsGreen+ cells at 48 h recovery after PTX treatment. N = 3. C The effect of knocking down RELA (left) or chemical inhibition of NFκB signaling (right) on the percentage of ZsGreen+ cells at 48 h recovery after PTX treatment. N = 3. D The effect of knocking down BIRC3 on the percentage of GFP+ HCT-116GC3AI cells after 24 h PTX treatment. N = 3. E The effect of knocking down RELA (upper) or chemical inhibition of NFκB signaling (lower) on the percentage of GFP+ HCT-116GC3AI cells after 24 h PTX treatment. N = 3. In all bar graphs, error bars represent the standard error of the mean. *P < 0.05. **P < 0.01. ***P < 0.001.

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