Fig. 6: Oxidative Phosphorylation and Glycolysis disrupted in efferocytic MSCs. | Cell Death & Disease

Fig. 6: Oxidative Phosphorylation and Glycolysis disrupted in efferocytic MSCs.

From: Efferocytosis by bone marrow mesenchymal stromal cells disrupts osteoblastic differentiation via mitochondrial remodeling

Fig. 6

A–D Mitochondrial oxygen consumption rate (OCR), glycolysis, and glycolytic capacity measured with the Seahorse XF technology of bone marrow-derived ST2 cells incubated with increasing dosage of end stage neutrophils (PMN). Graphs show actual data points (each point contains 8 technical replicates) and calculated Mean + SD. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001 (ANOVA). E–H Mitochondrial oxygen consumption rate (OCR), glycolysis, and glycolytic capacity measured with the Seahorse XF technology of ST2 cells challenged with excess neutrophils (1:10) and then sorted alongside controls into PMN +/−. Graphs show biological data points (each containing 8 technical replicates) and calculated Mean + SD. *p < 0.05, **p < 0.01, (ANOVA with post Tukey test).

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