Fig. 2: Loss of TP53 synergizes with c-MET to promote hepatocarcinogenesis in mice. | Cell Death & Disease

Fig. 2: Loss of TP53 synergizes with c-MET to promote hepatocarcinogenesis in mice.

From: Loss of TP53 cooperates with c-MET overexpression to drive hepatocarcinogenesis

Fig. 2

A Study design. B Gross images, H&E staining, and immunohistochemical staining of p53, CK19, HNF4a, and Ki67 in tumor lesions from c-MET/sgp53 mouse liver. C Western blotting analysis of lysates from normal liver and c-MET/sgp53 mouse HCCs. Scale bar: 200 μm (100×). H&E hematoxylin and eosin staining, CK19 cytokeratin 19, HNF4a hepatocyte nuclear factor 4α.

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