Fig. 3: RNA sequencing data show the activation of the MAPK signaling pathway in c-MET/sgp53 HCCs.
From: Loss of TP53 cooperates with c-MET overexpression to drive hepatocarcinogenesis

A Genetic dissimilarity among the samples in c-MET/sgp53 HCCs and normal liver as demonstrated by the heatmap. B KEGG analysis of upregulated DEGs in the c-MET/sgp53 HCCs as compared to normal livers. C KEGG analysis of overlapping up-regulated DEGs in c-MET/sgp53 HCCs and c-MET-high/TP53-null human HCCs. NL normal livers, ST surrounding tissues, DEG differentially expressed genes.