Fig. 4: Establishment of a stably passaged cell line (MP) derived from c-MET/sgp53 HCC.
From: Loss of TP53 cooperates with c-MET overexpression to drive hepatocarcinogenesis
A Western blotting analysis of lysates from normal liver and MP cells. B Cell viability analysis for MP cells treated with cabozantinib, niclosamide, and metformin. C Gross images of MP-derived xenografts from mice treated with cabozantinib, niclosamide, metformin, and vehicles. D Tumor volume of mice treated with cabozantinib and vehicles. D Tumor volume of mice treated with niclosamide, metformin, and vehicles. Data are shown as mean ± SD.
