Fig. 1: LMO2 is upregulated in AML and is related to prognosis.
From: LMO2 promotes the development of AML through interaction with transcription co-regulator LDB1
A Using the IGV visualization tool to compare the ChIP-Seq results of clinical samples of children with AML for H3K27Ac, the area near LMO2 was enriched, and there was a high possibility of super-enhancers. B Expression levels of LMO2 in common cancer cells in the CCLE database. C According to the The Cancer Genome Atlas (TCGA) database, patients with high LMO2 expression in Patients with AML have a lower survival rate. D Validated Western-blot data in AML cell lines, suggesting that LMO2 is expressed to varying degrees.
